Fire broke out at 388 Summer Ave. shortly before 6 a.m. Sixty-five firefighters were called to the two-alarm blaze before it was brought under control around 6:40 a.m.
One person jumped from a window to escape the blaze, according to media reports.
Firefighters also discovered a deceased male on the first floor of the home. A second person suffered serious injuries, while three others suffered minor injuries.
Two animals also died in the fire.
A total of seven adults were displaced.
The fire is under investigation.
Click here to follow Daily Voice West Milford and receive free news updates.